For seminar recording, please click here Talk Title: Dissecting intra-tumor heterogeneity by single cell RNA-seq Abstract: Each tumor is composed of diverse malignant, immune and stromal cells that interact with one another and collectively determine tumor biology and clinical phenotypes. Over the past nine years, we have been applying single cell RNA-seq (scRNA-seq) to […]
For seminar recording, please click here Talk Title: Systems analysis of ligand effects induced by chromosomal instability on the tumor ecosystem Abstract: Multicellular programs underly emergent phenotypes in health and disease. Yet, deciphering higher-order functional interactions amongst cell types remains a major challenge. Cell-to-cell communication often takes the form of ligands emanating from “donor” cells […]
For seminar recording, please click here Talk Title: Genomic landscapes of Breast Cancer (Racial/Ancestry) Disparities Abstract: Overview of the emerging findings from genome-wide studies of African-enriched cohorts of breast cancer patients. We will discuss results of multiple 'omic' approaches, including genotype associations, whole genome sequence characterizations and transcriptomic studies.