For seminar recording, please click here Talk Title: Detecting effects of alterations in chromosome structure on cancer cellular fitness Abstract: Structural variants—alterations in chromosome structure—affect far more of the cancer genome than any other type of genetic event. Indeed, large-scale aneuploidies were the first genetic alteration posited to contribute to cancer. Because of their complexity […]
Meeting Recording: https://web.microsoftstream.com/video/c84847fc-b1d2-4ec2-a7c3-5243f063cc3f Talk Title: Learning Interpretable Models on Complex Medical Data Abstract: Machine learning as a field has become more and more important due to the ubiquity of data collection in various disciplines. Coupled with this data collection is the hope that new discoveries or knowledge can be learned. My research spans both fundamental […]
For seminar recording, please click here Talk Title: Dissecting intra-tumor heterogeneity by single cell RNA-seq Abstract: Each tumor is composed of diverse malignant, immune and stromal cells that interact with one another and collectively determine tumor biology and clinical phenotypes. Over the past nine years, we have been applying single cell RNA-seq (scRNA-seq) to […]