To view the seminar recording, please click here Talk Title: Cellular plasticity and developmental constraints in tumorigenesis and drug resistance Abstract: Cellular plasticity is emerging as an important driving force underlying cancer progression and drug resistance. In this talk, I will discuss the concept of cancer cell states present in the tumor prior to treatment, […]

To view the seminar recording, please click here Talk Title: Deciphering tissue pathogenesis with spatial sequencing Abstract: Spatial and molecular characteristics determine tissue function, yet high-resolution methods to capture both concurrently are lacking. In recent years, we developed high-definition spatial transcriptomics and multi-omics technologies, which captures RNA, protein information or microbiota from histological tissue sections […]

To view the seminar recording, please click here Talk Title: Statistical approaches for deciphering gene programs in cancer cells across studies and mutational signatures across ancestries Abstract: Single-cell assays provide valuable insights into the biological processes active in cancer cells within and across tumor samples. However, the majority of single cell RNA-seq (scRNA-seq) studies only […]