For seminar recording, please click here Talk Title: Dissecting intra-tumor heterogeneity by single cell RNA-seq Abstract: Each tumor is composed of diverse malignant, immune and stromal cells that interact with one another and collectively determine tumor biology and clinical phenotypes. Over the past nine years, we have been applying single cell RNA-seq (scRNA-seq) to […]
For seminar recording click here Talk Title: Latent States of Brains and Behavior Abstract: New recording technologies are transforming neuroscience, allowing us to measure the spiking activity of thousands of neurons in freely behaving animals. These technologies offer exciting opportunities to link brain activity to behavioral output, but they also pose serious statistical challenges. Neural […]
For seminar recording, please click here Talk Title: Systems analysis of ligand effects induced by chromosomal instability on the tumor ecosystem Abstract: Multicellular programs underly emergent phenotypes in health and disease. Yet, deciphering higher-order functional interactions amongst cell types remains a major challenge. Cell-to-cell communication often takes the form of ligands emanating from “donor” cells […]