JianJiong Gao, PhD

Associate Attending
Contact
Desiree Lara Larad@mskcc.org

About

Dr. Gao’s research interests are rooted in the quest to harness the power of molecular and clinical data to accelerate cancer research and revolutionize cancer care. His primary focus is on building effective methods and infrastructure to bridge the gap between complex data and actionable insights for cancer researchers and clinicians. As an Associate Attending in the Computational Oncology Service and the Head of Engineering for the Cancer Data Science Initiative (CDSI) at Memorial Sloan Kettering Cancer Center, he lead a team to develop sophisticated methods and platforms to integrate multimodal real world patient data and apply advanced artificial intelligence (AI) methods to answer research and clinical questions. Notable projects co-led/founded by Dr. Gao include cBioPortal, OncoKB, Genome Nexus, and MSK MIND. These projects and new efforts in CDSI are geared towards creating a clinical decision support infrastructure that provides clinicians with data-driven insights into patients’ diseases, ultimately informing and enhancing clinical decisions.

Education

PhD

University of Missouri, Columbia, Missouri

Appointments

Computational Oncology, Department of Epidemiology & Biostatistics

Selected Publications

de Bruijn I, Kundra R, Mastrogiacomo B, Tran TN, Sikina L, Mazor T, Li X, Ochoa A, Zhao G, Lai B, Abeshouse A, Baiceanu D, Ciftci E, Dogrusoz U, Dufilie A, Erkoc Z, Garcia Lara E, Fu Z, Gross B, Haynes C, Heath A, Higgins D, Jagannathan P, Kalletla K, Kumari P, Lindsay J, Lisman A, Leenknegt B, Lukasse P, Madela D, Madupuri R, van Nierop P, Plantalech O, Quach J, Resnick AC, Rodenburg SYA, Satravada BA, Schaeffer F, Sheridan R, Singh J, Sirohi R, Sumer SO, van Hagen S, Wang A, Wilson M, Zhang H, Zhu K, Rusk N, Brown S, Lavery JA, Panageas KS, Rudolph JE, LeNoue-Newton ML, Warner JL, Guo X, Hunter-Zinck H, Yu TV, Pilai S, Nichols C, Gardos SM, Philip J; AACR Project GENIE BPC Core Team, AACR Project GENIE Consortium; Kehl KL, Riely GJ, Schrag D, Lee J, Fiandalo MV, Sweeney SM, Pugh TJ, Sander C, Cerami E, Gao J, Schultz N. Analysis and Visualization of Longitudinal Genomic and Clinical Data from the AACR Project GENIE Biopharma Collaborative in cBioPortal. Cancer Res. 2023 Dec 1;83(23):3861-3867. doi: 10.1158/0008-5472.CAN-23-0816. PMID: 37668528

de Bruijn I, Li X, Sumer SO, Gross B, Sheridan R, Ochoa A, Wilson M, Wang A, Zhang H, Lisman A, Abeshouse A, Zhang E, Thum A, Sadagopan A, Heins Z, Kandoth C, Rodenburg S, Tan S, Lukasse P, van Hagen S, Fijneman RJA, Meijer GA, Schultz N, Gao J. Genome Nexus: a comprehensive resource for the annotation and interpretation of genomic variants in cancer. JCO Clin Cancer Inform. 2022 Feb;6:e2100144. doi: 10.1200/CCI.21.00144. PMID: 35148171

Chakravarty D*, Gao J*, et al. OncoKB: A Precision Oncology Knowledge Base. JCO PO. 2017:1,1-16. PMCID: PMC5586540.Gao J, et al. Integrative analysis of complex cancer genomics and clinical profiles using the cBioPortal. Sci Signal. 2013 Apr 2;6(269):pl1. PMCID: PMC4160307.