Genetics and anatomy sculpt immune-cell partners of ovarian cancer was recently published in Nature. The most common type of ovarian cancer, called high-grade serous ovarian cancer (HGSOC), is challenging from a therapeutic perspective. By the time most individuals are diagnosed with this type of tumour, it has already spread (metastasized) from the primary site to distant regions, seeding cancer cells in multiple abdominal locations (intraperitoneal sites). At that point, symptoms arise because of an accumulation of peritoneal fluid in these areas. Writing in Nature, Vázquez-García et al. provide insights into metastatic ovarian cancer.
You can read the paper in Nature here.