Genetics and anatomy sculpt immune-cell partners of ovarian cancer was recently published in Nature. The most common type of ovarian cancer, called high-grade serous ovarian cancer (HGSOC), is challenging from a therapeutic perspective. By the time most individuals are diagnosed with this type of tumour, it has already spread (metastasized) from the primary site to...Read More

Dr. Sohrab Shah et al. published the paper Ovarian cancer mutational processes drive site-specific immune evasion in Nature. High-grade serous ovarian cancer (HGSOC) is an archetypal cancer of genomic instability patterned by distinct mutational processes, tumour heterogeneity and intraperitoneal spread. Immunotherapies have had limited efficacy in HGSOC, highlighting an unmet need to assess how mutational...Read More