For seminar recording, please click here Talk Title: Some mysteries about viruses and cancer Abstract: It has been estimated that 15%-20% of human cancers are attributable to infections, mostly by carcinogenic viruses. The incidence varies worldwide, with a majority affecting developing countries. Here, we present a comparative analysis of virus-positive and virus-negative tumors in nine […]
For seminar recording, please click here Talk Title: Leveraging mass balance and long DNA molecules to study structural variant mutational processes in cancer Abstract: Genome structure, like other physical phenomena, obeys the simple principle of mass balance. I will show how we can apply this principle algorithmically to assess what structural variants (SVs) are missing from […]
For seminar recording, please click here Talk Title: Using T2T-level comparative genomics to study repeat biology Abstract: Mobile elements and highly repetitive regions are potent sources of lineage-specific genomic innovation and are integral to the structure and function of eukaryotic cells. Recent efforts employing long-read based genome assembly, functional and repeat analyses across multiple marsupial […]
