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Dr. Adam Weiner published the paper Inferring replication timing and proliferation dynamics from single-cell DNA sequencing data. The study explores how dysregulated DNA replication is a cause and a consequence of aneuploidy in cancer, yet the interplay between copy number alterations (CNAs), replication timing (RT) and cell cycle dynamics remain understudied in aneuploid tumors. We...
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Dr. Nicholas Ceglia et al. published the paper Identification of transcriptional programs using dense vector representations defined by mutual information with GeneVector. A scalable framework for dimensionality reduction, GeneVector identifies transcriptional programs and classifies cell types. You can read the paper in Nature Communications here.
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