Phase and context shape the function of composite oncogenic mutations

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Research from Computational Oncology reports on the pervasive presence and function of composite mutations: two or more mutations to the same gene. They describe the myriad ways that these mutations interact to promote the development and progression of cancer.

Dr. Ed Reznik explains more about his lab’s recent paper on his Twitter.

Dr. Barry Taylor comments on this “unexpected cancer gene story” on his Twitter.

You may read the related paper by Gorelick et al. in Nature.